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[[Image:4eer.jpg|left|200px]]


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==Crystal structure of LOV2 domain of Arabidopsis thaliana phototropin 2 C426A mutant==
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<StructureSection load='4eer' size='340' side='right'caption='[[4eer]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4eer]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EER FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.753&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
{{STRUCTURE_4eer|  PDB=4eer  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eer OCA], [https://pdbe.org/4eer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eer RCSB], [https://www.ebi.ac.uk/pdbsum/4eer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eer ProSAT]</span></td></tr>
 
</table>
===Crystal structure of LOV2 domain of Arabidopsis thaliana phototropin 2 C426A mutant===
== Function ==
 
[https://www.uniprot.org/uniprot/PHOT2_ARATH PHOT2_ARATH] Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for photo-induced movements. Mediates calcium spiking of extra- and intracellular origins in response to blue light. Involved in hypocotyl phototropism. Contributes to the chloroplast accumulation in low blue light and mediates their translocation (avoidance response) at high fluence. Regulates stomata opening and photomorphogenesis response of leaf tissue. Not involved in hypocotyl elongation inhibition, anthocyanin accumulation or cotyledon opening.<ref>PMID:11371609</ref> <ref>PMID:11251116</ref> <ref>PMID:12821778</ref> <ref>PMID:15031408</ref> <ref>PMID:14982991</ref>
 
== References ==
==About this Structure==
<references/>
[[4eer]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EER OCA].  
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Large Structures]]
[[Category: Arvai, A S.]]
[[Category: Phototropin]]
[[Category: Christie, J M.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Getzoff, E D.]]
[[Category: Arvai AS]]
[[Category: Hartfield, K A.]]
[[Category: Christie JM]]
[[Category: Hitomi, K]]
[[Category: Getzoff ED]]
[[Category: Pratt, A J.]]
[[Category: Hartfield KA]]
[[Category: Tainer, J A.]]
[[Category: Hitomi K]]
[[Category: Blue light photoreceptor]]
[[Category: Pratt AJ]]
[[Category: Flavoprotein]]
[[Category: Tainer JA]]
[[Category: Lov]]
[[Category: Signaling protein]]

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