2lrq: Difference between revisions

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'''Unreleased structure'''


The entry 2lrq is ON HOLD
==Chemical Shift Assignment and Solution Structure of Fr822A from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822A==
 
<StructureSection load='2lrq' size='340' side='right'caption='[[2lrq]]' scene=''>
Authors: Lee, H., Lee, D., Kohan, E., Janjua, H., Xiao, R., Acton, T., Everett, J.K., Montelione, G., Prestegard, J.H., Northeast Structural Genomics Consortium (NESG)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2lrq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LRQ FirstGlance]. <br>
Description: Chemical Shift Assignment and Solution Structure of ChR145 from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822A
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lrq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lrq OCA], [https://pdbe.org/2lrq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lrq RCSB], [https://www.ebi.ac.uk/pdbsum/2lrq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lrq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EAF3_DROME EAF3_DROME] Part of the Tip60 chromatin-remodeling complex which is involved in DNA repair. Upon induction of DNA double-strand breaks, this complex acetylates phosphorylated H2AV in nucleosomes and exchanges it with unmodified H2AV.<ref>PMID:15528408</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Acton T]]
[[Category: Everett JK]]
[[Category: Janjua H]]
[[Category: Kohan E]]
[[Category: Lee D]]
[[Category: Lee H]]
[[Category: Montelione G]]
[[Category: Prestegard JH]]
[[Category: Xiao R]]

Latest revision as of 08:50, 15 May 2024

Chemical Shift Assignment and Solution Structure of Fr822A from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822AChemical Shift Assignment and Solution Structure of Fr822A from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822A

Structural highlights

2lrq is a 1 chain structure with sequence from Drosophila melanogaster. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

EAF3_DROME Part of the Tip60 chromatin-remodeling complex which is involved in DNA repair. Upon induction of DNA double-strand breaks, this complex acetylates phosphorylated H2AV in nucleosomes and exchanges it with unmodified H2AV.[1]

References

  1. ↑ Kusch T, Florens L, Macdonald WH, Swanson SK, Glaser RL, Yates JR 3rd, Abmayr SM, Washburn MP, Workman JL. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science. 2004 Dec 17;306(5704):2084-7. Epub 2004 Nov 4. PMID:15528408 doi:http://dx.doi.org/1103455
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