3vd1: Difference between revisions

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-[[Image:3vd1.jpg|left|200px]]
-<!--
+==structure of p73 DNA binding domain tetramer modulates p73 transactivation==
-The line below this paragraph, containing "STRUCTURE_3vd1", creates the "Structure Box" on the page.
+<StructureSection load='3vd1' size='340' side='right'caption='[[3vd1]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3vd1]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VD1 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_3vd1|  PDB=3vd1  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vd1 OCA], [https://pdbe.org/3vd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vd1 RCSB], [https://www.ebi.ac.uk/pdbsum/3vd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vd1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
-===structure of p73 DNA binding domain tetramer modulates p73 transactivation===
+==See Also==
+*[[P73|P73]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22474346}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22474346 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_22474346}}
-==About this Structure==
-[[3vd1]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VD1 OCA].
-==Reference==
-<ref group="xtra">PMID:022474346</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Ethayathulla, A S]]
+[[Category: Large Structures]]
-[[Category: Nguyen, S.]]
+[[Category: Ethayathulla AS]]
-[[Category: Tse, P W.]]
+[[Category: Nguyen S]]
-[[Category: Viadiu, H.]]
+[[Category: Tse PW]]
-[[Category: Antitumor protein-dna complex]]
+[[Category: Viadiu H]]
-[[Category: Beta-immunoglobulin-like fold]]
-[[Category: Protein dna complex]]
-[[Category: Tumour suppressor]]