4en0: Difference between revisions
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New page: '''Unreleased structure''' The entry 4en0 is ON HOLD Authors: Zhan, C., Liu, W., Patskovsky, Y., Ramagopal, U.A., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomic... |
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==Crystal structure of light== | |||
<StructureSection load='4en0' size='340' side='right'caption='[[4en0]], [[Resolution|resolution]] 2.59Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4en0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ugn 3ugn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EN0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4en0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4en0 OCA], [https://pdbe.org/4en0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4en0 RCSB], [https://www.ebi.ac.uk/pdbsum/4en0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4en0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. | |||
==See Also== | |||
*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]] | |||
*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Almo SC]] | |||
[[Category: Bonanno JB]] | |||
[[Category: Liu W]] | |||
[[Category: Nathenson SG]] | |||
[[Category: Patskovsky Y]] | |||
[[Category: Ramagopal UA]] | |||
[[Category: Zhan C]] | |||
Latest revision as of 18:05, 14 March 2024
Crystal structure of lightCrystal structure of light
Structural highlights
FunctionTNF14_HUMAN Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. See Also |
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