3u3y: Difference between revisions

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[[Image:3u3y.png|left|200px]]


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==Mouse TREX1 D200H mutant==
The line below this paragraph, containing "STRUCTURE_3u3y", creates the "Structure Box" on the page.
<StructureSection load='3u3y' size='340' side='right'caption='[[3u3y]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3u3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U3Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_3u3y|  PDB=3u3y  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3y OCA], [https://pdbe.org/3u3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u3y RCSB], [https://www.ebi.ac.uk/pdbsum/3u3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u3y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>


===Mouse TREX1 D200H mutant===
==See Also==
 
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 22071149 is the PubMed ID number.
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_22071149}}
 
==About this Structure==
[[3u3y]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U3Y OCA].
 
==Reference==
<ref group="xtra">PMID:022071149</ref><references group="xtra"/>
[[Category: Exodeoxyribonuclease III]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Bailey, S L.]]
[[Category: Bailey SL]]
[[Category: Harvey, S.]]
[[Category: Harvey S]]
[[Category: Hollis, T.]]
[[Category: Hollis T]]
[[Category: Perrino, F W.]]
[[Category: Perrino FW]]
[[Category: 3' exonuclease]]
[[Category: Homodimer]]
[[Category: Hydrolase-dna complex]]
[[Category: Rnase h fold]]

Latest revision as of 13:16, 1 March 2024

Mouse TREX1 D200H mutantMouse TREX1 D200H mutant

Structural highlights

3u3y is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.28Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TREX1_MOUSE Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.[1] [2]

See Also

References

  1. ↑ Mazur DJ, Perrino FW. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases. J Biol Chem. 1999 Jul 9;274(28):19655-60. PMID:10391904
  2. ↑ Mazur DJ, Perrino FW. Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins. J Biol Chem. 2001 May 18;276(20):17022-9. Epub 2001 Mar 6. PMID:11279105 doi:http://dx.doi.org/10.1074/jbc.M100623200

3u3y, resolution 2.28Å

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