3un9: Difference between revisions

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-[[Image:3un9.png|left|200px]]
-<!--
+==Crystal structure of an immune receptor==
-The line below this paragraph, containing "STRUCTURE_3un9", creates the "Structure Box" on the page.
+<StructureSection load='3un9' size='340' side='right'caption='[[3un9]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3un9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UN9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UN9 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
-{{STRUCTURE_3un9|  PDB=3un9  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3un9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3un9 OCA], [https://pdbe.org/3un9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3un9 RCSB], [https://www.ebi.ac.uk/pdbsum/3un9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3un9 ProSAT]</span></td></tr>
+</table>
-===Crystal structure of an immune receptor===
+== Function ==
+[https://www.uniprot.org/uniprot/NLRX1_HUMAN NLRX1_HUMAN] Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).<ref>PMID:18219313</ref> <ref>PMID:18200010</ref>
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22386589}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22386589 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_22386589}}
-==About this Structure==
-[[3un9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UN9 OCA].
-==Reference==
-<ref group="xtra">PMID:022386589</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Hong, M.]]
+[[Category: Large Structures]]
-[[Category: Wilson, I A.]]
+[[Category: Hong M]]
-[[Category: Yoon, S I.]]
+[[Category: Wilson IA]]
-[[Category: Antiviral signaling]]
+[[Category: Yoon SI]]
-[[Category: Ikk]]
-[[Category: Immune system]]
-[[Category: Mav]]
-[[Category: Traf6]]
-[[Category: Uqcrc2]]