4eb3: Difference between revisions

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-'''Unreleased structure'''
-The entry 4eb3 is ON HOLD
+==Crystal structure of IspH in complex with iso-HMBPP==
+<StructureSection load='4eb3' size='340' side='right'caption='[[4eb3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4eb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EB3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0O3:3-(HYDROXYMETHYL)BUT-3-EN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>0O3</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eb3 OCA], [https://pdbe.org/4eb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eb3 RCSB], [https://www.ebi.ac.uk/pdbsum/4eb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eb3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref>
-Authors: Wang, W., Wang, K., Span, I., Jauch, J., Bacher, A., Groll, M., Oldfield, E.
+==See Also==
+*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]]
-Description: Crystal structure of IspH in complex with iso-HMBPP
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli K-12]]
+[[Category: Large Structures]]
+[[Category: Bacher A]]
+[[Category: Groll M]]
+[[Category: Oldfield E]]
+[[Category: Span I]]
+[[Category: Wang K]]
+[[Category: Wang W]]