3ogq: Difference between revisions

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-[[Image:3ogq.png|left|200px]]
-<!--
+==Crystal Structure of 6s-98S FIV Protease with Lopinavir bound==
-The line below this paragraph, containing "STRUCTURE_3ogq", creates the "Structure Box" on the page.
+<StructureSection load='3ogq' size='340' side='right'caption='[[3ogq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ogq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OGQ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-{{STRUCTURE_3ogq|  PDB=3ogq  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ogq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ogq OCA], [https://pdbe.org/3ogq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ogq RCSB], [https://www.ebi.ac.uk/pdbsum/3ogq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ogq ProSAT]</span></td></tr>
+</table>
-===Crystal Structure of 6s-98S FIV Protease with Lopinavir bound===
+== Function ==
+[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_21636894}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 21636894 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_21636894}}
-==About this Structure==
-[[3ogq]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA].
 ==See Also==
-*[[Virus protease]]
+*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:021636894</ref><references group="xtra"/>
 [[Category: Feline immunodeficiency virus]]
-[[Category: Elder, J H.]]
+[[Category: Large Structures]]
-[[Category: Lin, Y C.]]
+[[Category: Elder JH]]
-[[Category: Perryman, A L.]]
+[[Category: Lin Y-C]]
-[[Category: Stout, C D.]]
+[[Category: Perryman AL]]
-[[Category: Aspartyl protease]]
+[[Category: Stout CD]]
-[[Category: Hiv-like fiv chimera]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]