4e5u: Difference between revisions

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New page: '''Unreleased structure''' The entry 4e5u is ON HOLD Authors: Tan, K., Joachimiak, G., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structures of Mtb ...
 
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'''Unreleased structure'''


The entry 4e5u is ON HOLD
==The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with thymidine monophosphate.==
<StructureSection load='4e5u' size='340' side='right'caption='[[4e5u]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4e5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E5U FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.812&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e5u OCA], [https://pdbe.org/4e5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e5u RCSB], [https://www.ebi.ac.uk/pdbsum/4e5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e5u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KTHY_PSEAE KTHY_PSEAE] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).


Authors: Tan, K., Joachimiak, G., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
==See Also==
 
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
Description: The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with thymidine monophosphate.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Jedrzejczak R]]
[[Category: Joachimiak A]]
[[Category: Joachimiak G]]
[[Category: Sacchettini J]]
[[Category: Tan K]]

Latest revision as of 09:55, 27 November 2024

The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with thymidine monophosphate.The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with thymidine monophosphate.

Structural highlights

4e5u is a 2 chain structure with sequence from Pseudomonas aeruginosa PAO1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.812Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KTHY_PSEAE Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).

See Also

4e5u, resolution 1.81Å

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