3t6c: Difference between revisions

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[[Image:3t6c.png|left|200px]]


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==Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg==
The line below this paragraph, containing "STRUCTURE_3t6c", creates the "Structure Box" on the page.
<StructureSection load='3t6c' size='340' side='right'caption='[[3t6c]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3t6c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pantoea_ananatis_LMG_20103 Pantoea ananatis LMG 20103]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T6C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
{{STRUCTURE_3t6c|  PDB=3t6c  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t6c OCA], [https://pdbe.org/3t6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t6c RCSB], [https://www.ebi.ac.uk/pdbsum/3t6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t6c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DGD_PANAM DGD_PANAM] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>


===Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg===
==See Also==
 
*[[Enolase 3D structures|Enolase 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[3t6c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pantoea_ananatis Pantoea ananatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6C OCA].
__TOC__
[[Category: Pantoea ananatis]]
</StructureSection>
[[Category: Almo, S C.]]
[[Category: Large Structures]]
[[Category: Bhosle, R.]]
[[Category: Pantoea ananatis LMG 20103]]
[[Category: Chowdhury, S.]]
[[Category: Almo SC]]
[[Category: EFI, Enzyme Function Initiative.]]
[[Category: Bhosle R]]
[[Category: Evans, B.]]
[[Category: Chowdhury S]]
[[Category: Gerlt, J A.]]
[[Category: Evans B]]
[[Category: Glenn, A Scott.]]
[[Category: Gerlt JA]]
[[Category: Hammonds, J.]]
[[Category: Hammonds J]]
[[Category: Hillerich, B.]]
[[Category: Hillerich B]]
[[Category: Imker, H J.]]
[[Category: Imker HJ]]
[[Category: Morisco, L L.]]
[[Category: Morisco LL]]
[[Category: Toro, R.]]
[[Category: Scott Glenn A]]
[[Category: Vetting, M W.]]
[[Category: Toro R]]
[[Category: Washington, E.]]
[[Category: Vetting MW]]
[[Category: Wasserman, S R.]]
[[Category: Washington E]]
[[Category: Zencheck, W D.]]
[[Category: Wasserman SR]]
[[Category: Enolase]]
[[Category: Zencheck WD]]
[[Category: Enzyme function intitiative]]
[[Category: Hydro-lyase]]
[[Category: Lyase]]
[[Category: Mannonate dehydratase related protein]]

Latest revision as of 16:18, 14 March 2024

Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mgCrystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg

Structural highlights

3t6c is a 2 chain structure with sequence from Pantoea ananatis LMG 20103. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.598Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DGD_PANAM Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).[1]

See Also

References

  1. ↑ Wichelecki DJ, Balthazor BM, Chau AC, Vetting MW, Fedorov AA, Fedorov EV, Lukk T, Patskovsky YV, Stead MB, Hillerich BS, Seidel RD, Almo SC, Gerlt JA. Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry. 2014 Apr 29;53(16):2722-31. doi: 10.1021/bi500264p. Epub 2014 Apr, 15. PMID:24697546 doi:http://dx.doi.org/10.1021/bi500264p

3t6c, resolution 1.60Å

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