4ddx: Difference between revisions

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'''Unreleased structure'''


The entry 4ddx is ON HOLD
==Thermotoga maritima reverse gyrase, primitive monoclinic form==
<StructureSection load='4ddx' size='340' side='right'caption='[[4ddx]], [[Resolution|resolution]] 4.17&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ddx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DDX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.17&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ddx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddx OCA], [https://pdbe.org/4ddx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ddx RCSB], [https://www.ebi.ac.uk/pdbsum/4ddx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RGYR_THEMA RGYR_THEMA] Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.


Authors: Rudolph, M.G., Klostermeier, D.
==See Also==
 
*[[Gyrase 3D Structures|Gyrase 3D Structures]]
Description:
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Klostermeier D]]
[[Category: Rudolph MG]]

Latest revision as of 17:33, 14 March 2024

Thermotoga maritima reverse gyrase, primitive monoclinic formThermotoga maritima reverse gyrase, primitive monoclinic form

Structural highlights

4ddx is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 4.17Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RGYR_THEMA Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.

See Also

4ddx, resolution 4.17Å

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