3vfq: Difference between revisions

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New page: '''Unreleased structure''' The entry 3vfq is ON HOLD Authors: Karlberg, T., Thorsell, A.G., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Ekblad, T., Weigelt, J., Schuler, H., Structura...
 
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'''Unreleased structure'''


The entry 3vfq is ON HOLD
==Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoribose==
<StructureSection load='3vfq' size='340' side='right'caption='[[3vfq]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vfq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VFQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AR6:[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL+[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL]+HYDROGEN+PHOSPHATE'>AR6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfq OCA], [https://pdbe.org/3vfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vfq RCSB], [https://www.ebi.ac.uk/pdbsum/3vfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.


Authors: Karlberg, T., Thorsell, A.G., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Ekblad, T., Weigelt, J., Schuler, H., Structural Genomics Consortium (SGC)
==See Also==
 
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
Description: HUMAN PARP14 (ARTD8, BAL2) -MACRO DOMAINS 1 AND 2 IN COMPLEX WITH ADENOSINE-5-DIPHOSPHORIBOSE
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: Ekblad T]]
[[Category: Karlberg T]]
[[Category: Schuler H]]
[[Category: Thorsell AG]]
[[Category: Weigelt J]]

Latest revision as of 17:27, 14 March 2024

Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoriboseHuman PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoribose

Structural highlights

3vfq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PAR14_HUMAN Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.

See Also

3vfq, resolution 2.80Å

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