3v5r: Difference between revisions
Jump to navigation
Jump to search
m Protected "3v5r" [edit=sysop:move=sysop] |
No edit summary |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
The | ==Crystal structure of the unliganded form of Gal3p== | ||
<StructureSection load='3v5r' size='340' side='right'caption='[[3v5r]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3v5r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V5R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.099Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v5r OCA], [https://pdbe.org/3v5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v5r RCSB], [https://www.ebi.ac.uk/pdbsum/3v5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v5r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GAL3_YEAST GAL3_YEAST] The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease. | |||
==See Also== | |||
*[[Gal3-Gal80-Gal4|Gal3-Gal80-Gal4]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: He H]] | |||
[[Category: Joshua-Tor L]] | |||
[[Category: Kumar PR]] | |||
[[Category: Lavy T]] | |||
Latest revision as of 17:18, 14 March 2024
Crystal structure of the unliganded form of Gal3pCrystal structure of the unliganded form of Gal3p
Structural highlights
FunctionGAL3_YEAST The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease. See Also |
| ||||||||||||||||||