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==Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus== | |||
<StructureSection load='3v1h' size='340' side='right'caption='[[3v1h]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3v1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V1H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v1h OCA], [https://pdbe.org/3v1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v1h RCSB], [https://www.ebi.ac.uk/pdbsum/3v1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v1h ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor. | |||
==See Also== | |||
*[[Phospholipase C|Phospholipase C]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus subsp. aureus str. Newman]] | |||
[[Category: Cheng J]] | |||
[[Category: Goldstein RI]] | |||
[[Category: Roberts MF]] | |||
[[Category: Stec B]] | |||
Latest revision as of 17:14, 14 March 2024
Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureusStructure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus
Structural highlights
FunctionPLC_STAAE Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor. See Also |
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