3igs: Difference between revisions

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[[Image:3igs.png|left|200px]]


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==Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase==
The line below this paragraph, containing "STRUCTURE_3igs", creates the "Structure Box" on the page.
<StructureSection load='3igs' size='340' side='right'caption='[[3igs]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3igs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IGS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16G:N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE'>16G</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-->
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_3igs|  PDB=3igs  |  SCENE=  }}
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanE2, STM3337 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acylglucosamine-6-phosphate_2-epimerase N-acylglucosamine-6-phosphate 2-epimerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.9 5.1.3.9] </span></td></tr>
===Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase===
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3igs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3igs OCA], [https://pdbe.org/3igs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3igs RCSB], [https://www.ebi.ac.uk/pdbsum/3igs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3igs ProSAT], [https://www.topsan.org/Proteins/CSGID/3igs TOPSAN]</span></td></tr>
 
</table>
 
== Function ==
==About this Structure==
[[https://www.uniprot.org/uniprot/NANE2_SALTY NANE2_SALTY]] Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential).
[[3igs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGS OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/3igs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3igs ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus typhimurium loeffler 1892]]
[[Category: Large Structures]]
[[Category: N-acylglucosamine-6-phosphate 2-epimerase]]
[[Category: N-acylglucosamine-6-phosphate 2-epimerase]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Category: Anderson, S M]]
[[Category: Anderson, S M.]]
[[Category: Anderson, W F]]
[[Category: Anderson, W F.]]
[[Category: Structural genomic]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Gordon, E]]
[[Category: Gordon, E.]]
[[Category: Papazisi, L]]
[[Category: Papazisi, L.]]
[[Category: Savchenko, A]]
[[Category: Savchenko, A.]]
[[Category: Skarina, T]]
[[Category: Skarina, T.]]
[[Category: Wawrzak, Z]]
[[Category: Wawrzak, Z.]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Energy metabolism]]
[[Category: Energy metabolism]]
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Salmonella]]
[[Category: Salmonella]]
[[Category: Structural genomic]]
[[Category: Sugar]]
[[Category: Sugar]]

Latest revision as of 06:32, 21 April 2022

Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimeraseStructure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase

Structural highlights

3igs is a 2 chain structure with sequence from "bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
NonStd Res:
Gene:nanE2, STM3337 ("Bacillus typhimurium" Loeffler 1892)
Activity:N-acylglucosamine-6-phosphate 2-epimerase, with EC number 5.1.3.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[NANE2_SALTY] Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3igs, resolution 1.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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