3psh: Difference between revisions

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[[Image:3psh.jpg|left|200px]]


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==Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate)==
The line below this paragraph, containing "STRUCTURE_3psh", creates the "Structure Box" on the page.
<StructureSection load='3psh' size='340' side='right'caption='[[3psh]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3psh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MOO:MOLYBDATE+ION'>MOO</scene></td></tr>
{{STRUCTURE_3psh|  PDB=3psh  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psh OCA], [https://pdbe.org/3psh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psh RCSB], [https://www.ebi.ac.uk/pdbsum/3psh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psh ProSAT]</span></td></tr>
 
</table>
===Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate)===
== Function ==
 
[https://www.uniprot.org/uniprot/MOLA_HAEIN MOLA_HAEIN] Part of the ABC transporter complex MolBCA involved in molybdate import (PubMed:22078568, PubMed:24722984). Functions as a low-affinity molybdate transporter (PubMed:24722984). Binds to both molybdate and tungstate, but not to sulfate or phosphate (PubMed:22078568).<ref>PMID:22078568</ref> <ref>PMID:24722984</ref>
 
== References ==
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{{ABSTRACT_PUBMED_22078568}}
 
==About this Structure==
[[3psh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSH OCA].  
 
==Reference==
<ref group="xtra">PMID:022078568</ref><references group="xtra"/>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Lee, A.]]
[[Category: Large Structures]]
[[Category: Pinkett, H W.]]
[[Category: Lee A]]
[[Category: Rees, D C.]]
[[Category: Pinkett HW]]
[[Category: Tirado-Lee, L.]]
[[Category: Rees DC]]
[[Category: Metal transport]]
[[Category: Tirado-Lee L]]
[[Category: Molybdate binding protein]]
[[Category: Periplasmic binding protein]]
[[Category: Substrate binding protein]]

Latest revision as of 13:43, 21 February 2024

Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate)Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate)

Structural highlights

3psh is a 1 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MOLA_HAEIN Part of the ABC transporter complex MolBCA involved in molybdate import (PubMed:22078568, PubMed:24722984). Functions as a low-affinity molybdate transporter (PubMed:24722984). Binds to both molybdate and tungstate, but not to sulfate or phosphate (PubMed:22078568).[1] [2]

References

  1. ↑ Tirado-Lee L, Lee A, Rees DC, Pinkett HW. Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA. Structure. 2011 Nov 9;19(11):1701-10. PMID:22078568 doi:10.1016/j.str.2011.10.004
  2. ↑ Rice AJ, Harrison A, Alvarez FJ, Davidson AL, Pinkett HW. Small substrate transport and mechanism of a molybdate ATP binding cassette transporter in a lipid environment. J Biol Chem. 2014 May 23;289(21):15005-13. PMID:24722984 doi:10.1074/jbc.M114.563783

3psh, resolution 1.50Å

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