3uld: Difference between revisions

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New page: '''Unreleased structure''' The entry 3uld is ON HOLD Authors: Gan, J.H., Abdur, R., Huang, Z. Description: High resolution structure of DNA/RNA hybrid in complex with RNase H catalytic...
 
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'''Unreleased structure'''


The entry 3uld is ON HOLD
==High resolution structure of DNA/RNA hybrid in complex with RNase H catalytic domain D132N mutant==
<StructureSection load='3uld' size='340' side='right'caption='[[3uld]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3uld]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ULD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ULD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGN:2-DEOXYGUANOSINE-3,5-DIPHOSPHATE'>PGN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uld OCA], [https://pdbe.org/3uld PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uld RCSB], [https://www.ebi.ac.uk/pdbsum/3uld PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uld ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>


Authors: Gan, J.H., Abdur, R., Huang, Z.
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
Description: High resolution structure of DNA/RNA hybrid in complex with RNase H catalytic domain D132N mutant
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Alkalihalobacillus halodurans]]
[[Category: Large Structures]]
[[Category: Abdur R]]
[[Category: Gan JH]]
[[Category: Huang Z]]

Latest revision as of 17:01, 14 March 2024

High resolution structure of DNA/RNA hybrid in complex with RNase H catalytic domain D132N mutantHigh resolution structure of DNA/RNA hybrid in complex with RNase H catalytic domain D132N mutant

Structural highlights

3uld is a 3 chain structure with sequence from Alkalihalobacillus halodurans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNH1_HALH5 Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.[1]

See Also

References

  1. Nowotny M, Gaidamakov SA, Crouch RJ, Yang W. Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis. Cell. 2005 Jul 1;121(7):1005-16. PMID:15989951 doi:http://dx.doi.org/10.1016/j.cell.2005.04.024

3uld, resolution 1.60Å

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