1lv2: Difference between revisions

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[[Image:1lv2.png|left|200px]]


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==Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids==
The line below this paragraph, containing "STRUCTURE_1lv2", creates the "Structure Box" on the page.
<StructureSection load='1lv2' size='340' side='right'caption='[[1lv2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
{{STRUCTURE_1lv2|  PDB=1lv2  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv2 OCA], [https://pdbe.org/1lv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv2 ProSAT]</span></td></tr>
 
</table>
===Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids===
== Function ==
 
[https://www.uniprot.org/uniprot/HNF4G_HUMAN HNF4G_HUMAN] Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12220494}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12220494 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv2_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12220494}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1lv2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV2 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv2 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:012220494</ref><references group="xtra"/>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Davis, R G.]]
[[Category: Large Structures]]
[[Category: Johnson, R.]]
[[Category: Davis RG]]
[[Category: Miller, A B.]]
[[Category: Johnson R]]
[[Category: Moore, J T.]]
[[Category: Miller AB]]
[[Category: Sefler, A.]]
[[Category: Moore JT]]
[[Category: Shearer, B.]]
[[Category: Sefler A]]
[[Category: Spitzer, T.]]
[[Category: Shearer B]]
[[Category: Williams, S P.]]
[[Category: Spitzer T]]
[[Category: Willson, T M.]]
[[Category: Williams SP]]
[[Category: Wisely, B.]]
[[Category: Willson TM]]
[[Category: Diabetes]]
[[Category: Wisely B]]
[[Category: Fatty acid]]
[[Category: Hnf4]]
[[Category: Mody]]
[[Category: Nuclear receptor]]
[[Category: Transcription]]
[[Category: Transcription factor]]

Latest revision as of 10:36, 14 February 2024

Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty AcidsHepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids

Structural highlights

1lv2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HNF4G_HUMAN Transcription factor. Has a lower transcription activation potential than HNF4-alpha.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1lv2, resolution 2.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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