3poo: Difference between revisions
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==human cAMP-dependent protein kinase in complex with an inhibitor== | |||
<StructureSection load='3poo' size='340' side='right'caption='[[3poo]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3poo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3POO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUD:(2S,3S)-BUTANE-2,3-DIOL'>BUD</scene>, <scene name='pdbligand=S69:N-[(E)-(2,4-DIHYDROXY-6-METHYLPHENYL)METHYLIDENE]-2-(3-METHOXYPHENYL)ACETOHYDRAZIDE'>S69</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3poo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3poo OCA], [https://pdbe.org/3poo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3poo RCSB], [https://www.ebi.ac.uk/pdbsum/3poo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3poo ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. | |||
==See Also== | |||
*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Heine A]] | |||
[[Category: Klebe G]] | |||
[[Category: Koester H]] | |||
Latest revision as of 12:34, 30 October 2024
human cAMP-dependent protein kinase in complex with an inhibitorhuman cAMP-dependent protein kinase in complex with an inhibitor
Structural highlights
FunctionIPKA_HUMAN Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. See Also |
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