2pfm: Difference between revisions

New page: left|200px<br /><applet load="2pfm" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pfm, resolution 2.00Å" /> '''Crystal Structure of...
 
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[[Image:2pfm.gif|left|200px]]<br /><applet load="2pfm" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pfm, resolution 2.00&Aring;" />
'''Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis'''<br />


==About this Structure==
==Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis==
2PFM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] with <scene name='pdbligand=MLI:'>MLI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Adenylosuccinate_lyase Adenylosuccinate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.2.2 4.3.2.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFM OCA].  
<StructureSection load='2pfm' size='340' side='right'caption='[[2pfm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Adenylosuccinate lyase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2pfm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfm OCA], [https://pdbe.org/2pfm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfm RCSB], [https://www.ebi.ac.uk/pdbsum/2pfm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A6L8PR48_BACAN A0A6L8PR48_BACAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pf/2pfm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pfm ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Baumgart, M.]]
[[Category: Baumgart M]]
[[Category: Blagova, E.V.]]
[[Category: Blagova EV]]
[[Category: Levdikov, V.M.]]
[[Category: Levdikov VM]]
[[Category: Moroz, O.V.]]
[[Category: Moroz OV]]
[[Category: Wilkinson, A.J.]]
[[Category: Wilkinson AJ]]
[[Category: Wilson, K.S.]]
[[Category: Wilson KS]]
[[Category: MLI]]
[[Category: adenylosuccinate lyase]]
[[Category: ba0290]]
[[Category: bacillus anthracis]]
[[Category: purb]]
[[Category: purine biosynthesis]]
 
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