3p8f: Difference between revisions

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-[[Image:3p8f.jpg|left|200px]]
-<!--
+==Crystal Structure of MT-SP1 in complex with SFTI-1==
-The line below this paragraph, containing "STRUCTURE_3p8f", creates the "Structure Box" on the page.
+<StructureSection load='3p8f' size='340' side='right'caption='[[3p8f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3p8f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P8F FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
-{{STRUCTURE_3p8f|  PDB=3p8f  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p8f OCA], [https://pdbe.org/3p8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p8f RCSB], [https://www.ebi.ac.uk/pdbsum/3p8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p8f ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN] Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:[https://omim.org/entry/610765 610765]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.<ref>PMID:17273967</ref>
+== Function ==
+[https://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN] Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
-===Crystal Structure of MT-SP1 in complex with SFTI-1===
+==See Also==
+*[[Matriptase 3D structures|Matriptase 3D structures]]
+*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
-<!--
+== References ==
-The line below this paragraph, {{ABSTRACT_PUBMED_21693064}}, adds the Publication Abstract to the page
+<references/>
-(as it appears on PubMed at http://www.pubmed.gov), where 21693064 is the PubMed ID number.
+__TOC__
--->
+</StructureSection>
-{{ABSTRACT_PUBMED_21693064}}
+[[Category: Helianthus annuus]]
-==About this Structure==
-[[3p8f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P8F OCA].
-==Reference==
-<ref group="xtra">PMID:021693064</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Matriptase]]
+[[Category: Large Structures]]
-[[Category: Chen, L.]]
+[[Category: Chen L]]
-[[Category: Huang, M.]]
+[[Category: Huang M]]
-[[Category: Yuan, C.]]
+[[Category: Yuan C]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Protein-inhibitor complex]]