3s14: Difference between revisions

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==RNA Polymerase II Initiation Complex with a 6-nt RNA==
The line below this paragraph, containing "STRUCTURE_3s14", creates the "Structure Box" on the page.
<StructureSection load='3s14' size='340' side='right'caption='[[3s14]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3s14]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S14 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3s14|  PDB=3s14  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s14 OCA], [https://pdbe.org/3s14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s14 RCSB], [https://www.ebi.ac.uk/pdbsum/3s14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s14 ProSAT]</span></td></tr>
 
</table>
===RNA Polymerase II Initiation Complex with a 6-nt RNA===
== Function ==
 
[https://www.uniprot.org/uniprot/RPB3_YEAST RPB3_YEAST] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. Seems to be involved in transcription termination.
 
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</StructureSection>
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 21798951 is the PubMed ID number.
[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Bushnell DA]]
{{ABSTRACT_PUBMED_21798951}}
[[Category: Huang X]]
 
[[Category: Kornberg RD]]
==About this Structure==
[[Category: Liu X]]
[[3s14]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S14 OCA].  
[[Category: Silva DA]]
 
==Reference==
<ref group="xtra">PMID:021798951</ref><references group="xtra"/>
[[Category: DNA-directed RNA polymerase]]
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Bushnell, D A.]]
[[Category: Huang, X.]]
[[Category: Kornberg, R D.]]
[[Category: Liu, X.]]
[[Category: Silva, D A.]]
[[Category: Initiation complex]]
[[Category: Rna polymerase ii]]
[[Category: Transcription-rna-dna complex]]

Latest revision as of 15:42, 14 March 2024

RNA Polymerase II Initiation Complex with a 6-nt RNARNA Polymerase II Initiation Complex with a 6-nt RNA

Structural highlights

3s14 is a 10 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.85Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPB3_YEAST DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. Seems to be involved in transcription termination.

3s14, resolution 2.85Å

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