Methyl-accepting chemotaxis protein: Difference between revisions

New page: left|200px|thumb|Crystal Structure of Methyl-accepting chemotaxis protein [[1xbn]] {{STRUCTURE_1xbn| PDB=1xbn | SIZE=300| SCENE= |right|CAPTION=Methyl-accepting chemot...
 
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[[Image:1xbn.png|left|200px|thumb|Crystal Structure of Methyl-accepting chemotaxis protein [[1xbn]]]]
{{STRUCTURE_1xbn|  PDB=1xbn  | SIZE=300| SCENE=Methyl-accepting_chemotaxis_protein/Cv/1 |right|CAPTION=Methyl-accepting chemotaxis protein with Fe-protoporphyrin IX + O2 [[1xbn]] }}
{{STRUCTURE_1xbn|  PDB=1xbn  | SIZE=300| SCENE= |right|CAPTION=Methyl-accepting chemotaxis protein with Fe-protoporphyrin IX + O2 [[1xbn]] }}


[[Methyl-accepting chemotaxis protein]] (MCP) are proteins of the inner cytoplasmic face of bacterial plasma membrane with which the receptors of the outer face interact.  MCP undergo reversible methylation as part of the adaptation to the signal.  MCP which are NO sensing contain a heme-NO and oxygen-binding domain (H-NOX). The images at the left and at the right correspond to one representative MCP, ''i.e.'' the crystal structure of Methyl-accepting chemotaxis protein from ''Thermoanaerobacter tengcongensis'' ([[3hbt]]).
[[Methyl-accepting chemotaxis protein]] (MCP) are proteins of the inner cytoplasmic face of bacterial plasma membrane with which the receptors of the outer face interact.  MCP undergo reversible methylation as part of the adaptation to the signal.  MCP which are NO sensing contain a heme-NO and oxygen-binding domain (H-NOX). For more details see [[Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor]].


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== 3D Structures of Methyl-accepting chemotaxis protein ==
== 3D Structures of Methyl-accepting chemotaxis protein ==


3g67 – TmMCP – Thermotoga maritima
[[3g67]] – TmMCP – ''Thermotoga maritima''<br />
3g6b - TmMCP (mutant)
[[3g6b]] - TmMCP (mutant)<br />
2ch7 – TmMCP cytoplasmic domain
[[2ch7]] – TmMCP cytoplasmic domain<br />
3c8c - MCP N terminal – Vibrio cholerae
[[3c8c]] - MCP N terminal – ''Vibrio cholerae''<br />
2qhx - MCP N terminal – Vibrio parahaemolyticus
[[2qhx]] - MCP N terminal – ''Vibrio parahaemolyticus''<br />
2d4u – EcMCP ligand-binding domain (mutant) – Eschericia coli
[[2d4u]] – EcMCP ligand-binding domain (mutant) – ''Eschericia coli''<br />
1qu7 - EcMCP  I cytoplasmic domain
[[1qu7]] - EcMCP  I cytoplasmic domain<br />
1jmw - MCP II ligand-binding domain (mutant) – Salmonella typhimurium
[[1jmw]] - MCP II ligand-binding domain (mutant) – ''Salmonella typhimurium''<br />


Heme-containing MCP
===Heme-containing MCP===


3sj5 – MCP (mutant) with Fe-protoporphyrin IX – Caldanaerobacter subterraneus
[[3sj5]] – MCP (mutant) with Fe-protoporphyrin IX – ''Caldanaerobacter subterraneus''<br />
3nvr, 3nvu, 3iqb, 3eee – TtMCP N terminal (mutant) with Fe-protoporphyrin IX + O2 – ''Thermoanaerobacter tengcongensis''
[[3nvr]], [[3nvu]], [[3iqb]], [[3eee]] – TtMCP N terminal (mutant) with Fe-protoporphyrin IX + O2 – ''Thermoanaerobacter tengcongensis''<br />
1xbn - TtMCP with Fe-protoporphyrin IX + O2
[[1xbn]] - TtMCP with Fe-protoporphyrin IX + O2<br />
1u4h, 1u55, 1u56 - TtMCP H-NOX domain with Fe-protoporphyrin IX + O2
[[1u4h]], [[1u55]], 1u56 - TtMCP H-NOX domain with Fe-protoporphyrin IX + O2<br />
3lah, 3lai - TtMCP N terminal (mutant) with Fe-protoporphyrin IX + imidazole
[[3lah]], [[3lai]] - TtMCP N terminal (mutant) with Fe-protoporphyrin IX + imidazole<br />
3m0b - TtMCP N terminal with Ru-mesoporphyrin IX
[[3m0b]] - TtMCP N terminal with Ru-mesoporphyrin IX<br />
 
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Alexander Berchansky, Michal Harel