3ren: Difference between revisions

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-[[Image:3ren.png|left|200px]]
-<!--
+==CPF_2247, a novel alpha-amylase from Clostridium perfringens==
-The line below this paragraph, containing "STRUCTURE_3ren", creates the "Structure Box" on the page.
+<StructureSection load='3ren' size='340' side='right'caption='[[3ren]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ren]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3REN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3REN FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_3ren|  PDB=3ren  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ren FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ren OCA], [https://pdbe.org/3ren PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ren RCSB], [https://www.ebi.ac.uk/pdbsum/3ren PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ren ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A0H2YP60_CLOP1 A0A0H2YP60_CLOP1]
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+CPF_2247 from Clostridium perfringens ATCC 13124 was identified as a putative carbohydrate-active enzyme by its low sequence identity to endo-beta-1,4-glucanases belonging to family 8 of the glycoside hydrolase classification. The X-ray crystal structure of CPF_2247 determined to 2.0 A resolution by single-wavelength anomalous dispersion using seleno-methionine-substituted protein revealed an (alpha/alpha)(6) barrel fold. A large cleft on the surface of the protein contains residues that are structurally conserved with key elements of the catalytic machinery in clan GH-M glycoside hydrolases. Assessment of CPF_2247 as a carbohydrate-active enzyme disclosed alpha-glucanase activity on amylose, glycogen, and malto-oligosaccharides.
-===CPF_2247, a novel alpha-amylase from Clostridium perfringens===
+Structural analysis of CPF_2247, a novel alpha-amylase from Clostridium perfringens.,Ficko-Blean E, Stuart CP, Boraston AB Proteins. 2011 Oct;79(10):2771-7. doi: 10.1002/prot.23116. Epub 2011 Aug 26. PMID:21905105<ref>PMID:21905105</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3ren" style="background-color:#fffaf0;"></div>
-==About this Structure==
+==See Also==
-[[3ren]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3REN OCA].
+*[[Amylase 3D structures|Amylase 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Clostridium perfringens]]
-[[Category: Boraston, A B.]]
+[[Category: Large Structures]]
-[[Category: Ficko-Blean, E.]]
+[[Category: Boraston AB]]
-[[Category: Stuart, C P.]]
+[[Category: Ficko-Blean E]]
-[[Category: Alpha-amylase]]
+[[Category: Stuart CP]]
-[[Category: Hydrolase]]