2gsh: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2gsh.gif|left|200px]]<br /><applet load="2gsh" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2gsh, resolution 2.393&Aring;" />
-'''Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium'''<br />
-==About this Structure==
+==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium==
-GSH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA].
+<StructureSection load='2gsh' size='340' side='right'caption='[[2gsh]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
-[[Category: L-rhamnonate dehydratase]]
+== Structural highlights ==
-[[Category: Salmonella typhimurium]]
+<table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GSH FirstGlance]. <br>
-[[Category: Single protein]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.393&#8491;</td></tr>
-[[Category: Adams, J.M.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Almo, S.C.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [https://pdbe.org/2gsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [https://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gsh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr>
-[[Category: Burley, S.K.]]
+</table>
-[[Category: Dickey, M.]]
+== Function ==
-[[Category: Gerlt, J.]]
+[https://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref>
-[[Category: Malashkevich, V.N.]]
+== Evolutionary Conservation ==
-[[Category: NYSGXRC, New.York.Structural.GenomiX.Research.Consortium.]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Patskovsky, Y.]]
+Check<jmol>
-[[Category: Sauder, J.M.]]
+  <jmolCheckbox>
-[[Category: Wasserman, S.R.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gsh_consurf.spt"</scriptWhenChecked>
-[[Category: GOL]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: MG]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: enolase]]
+  </jmolCheckbox>
-[[Category: new york structural genomix research consortium]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gsh ConSurf].
-[[Category: nysgxrc]]
+<div style="clear:both"></div>
-[[Category: protein structure initiative]]
+== References ==
-[[Category: psi]]
+<references/>
-[[Category: structural genomics]]
+__TOC__
+</StructureSection>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 20:07:04 2008''
+[[Category: Large Structures]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
+[[Category: Adams JM]]
+[[Category: Almo SC]]
+[[Category: Burley SK]]
+[[Category: Dickey M]]
+[[Category: Gerlt J]]
+[[Category: Malashkevich VN]]
+[[Category: Patskovsky Y]]
+[[Category: Sauder JM]]
+[[Category: Wasserman SR]]