1k8c: Difference between revisions

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[[Image:1k8c.png|left|200px]]


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==Crystal structure of dimeric xylose reductase in complex with NADP(H)==
The line below this paragraph, containing "STRUCTURE_1k8c", creates the "Structure Box" on the page.
<StructureSection load='1k8c' size='340' side='right'caption='[[1k8c]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1k8c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Yamadazyma_tenuis Yamadazyma tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K8C FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_1k8c|  PDB=1k8c  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k8c OCA], [https://pdbe.org/1k8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k8c RCSB], [https://www.ebi.ac.uk/pdbsum/1k8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k8c ProSAT]</span></td></tr>
 
</table>
===Crystal structure of dimeric xylose reductase in complex with NADP(H)===
== Function ==
 
[https://www.uniprot.org/uniprot/XYL1_CANTE XYL1_CANTE] Reduces D-xylose into xylitol. Has a preference for NADPH, but can also utilize NADH as cosubstrate.
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/1k8c_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12102621}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1k8c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_tenuis Candida tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8C OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k8c ConSurf].
 
<div style="clear:both"></div>
==See Also==
__TOC__
*[[Group:SMART:2010 Pingry SMART Team]]
</StructureSection>
 
[[Category: Large Structures]]
==Reference==
[[Category: Yamadazyma tenuis]]
<ref group="xtra">PMID:012102621</ref><references group="xtra"/>
[[Category: Kavanagh KL]]
[[Category: Aldehyde reductase]]
[[Category: Klimacek M]]
[[Category: Candida tenuis]]
[[Category: Nidetzky B]]
[[Category: Kavanagh, K L.]]
[[Category: Wilson DK]]
[[Category: Klimacek, M.]]
[[Category: Nidetzky, B.]]
[[Category: Wilson, D K.]]
[[Category: Aldo-keto reductase]]
[[Category: Beta-alpha barrel]]
[[Category: Oxidoreductase]]

Latest revision as of 10:44, 7 February 2024

Crystal structure of dimeric xylose reductase in complex with NADP(H)Crystal structure of dimeric xylose reductase in complex with NADP(H)

Structural highlights

1k8c is a 4 chain structure with sequence from Yamadazyma tenuis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

XYL1_CANTE Reduces D-xylose into xylitol. Has a preference for NADPH, but can also utilize NADH as cosubstrate.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1k8c, resolution 2.10Å

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OCA
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