3qi4: Difference between revisions

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[[Image:3qi4.jpg|left|200px]]


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==Crystal structure of PDE9A(Q453E) in complex with IBMX==
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<StructureSection load='3qi4' size='340' side='right'caption='[[3qi4]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3qi4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QI4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IBM:3-ISOBUTYL-1-METHYLXANTHINE'>IBM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3qi4|  PDB=3qi4  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qi4 OCA], [https://pdbe.org/3qi4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qi4 RCSB], [https://www.ebi.ac.uk/pdbsum/3qi4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qi4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDE9A_HUMAN PDE9A_HUMAN] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.<ref>PMID:18757755</ref>


===Crystal structure of PDE9A(Q453E) in complex with IBMX===
==See Also==
 
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_21483814}}
 
==About this Structure==
[[3qi4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QI4 OCA].
 
==Reference==
<ref group="xtra">PMID:21483814</ref><references group="xtra"/>
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hou, J.]]
[[Category: Large Structures]]
[[Category: Ke, H.]]
[[Category: Hou J]]
[[Category: Liu, M.]]
[[Category: Ke H]]
[[Category: Lou, H.]]
[[Category: Liu M]]
[[Category: Xu, J.]]
[[Category: Lou H]]
[[Category: Zhao, R.]]
[[Category: Xu J]]
[[Category: Zhao R]]

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