1wn6: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1wn6.png|left|200px]]
-<!--
+==Crystal Structure of Blasticidin S Deaminase (BSD) Complexed with Tetrahedral Intermediate of Blasticidin S==
-The line below this paragraph, containing "STRUCTURE_1wn6", creates the "Structure Box" on the page.
+<StructureSection load='1wn6' size='340' side='right'caption='[[1wn6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1wn6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WN6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=BST:6-(4-AMINO-4-HYDROXY-2-OXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-3-[3-AMINO-5-(N-METHYL-GUANIDINO)-PENT+ANOYLAMINO]-3,6-DIHYDRO-2H-PYRAN-2-CARBOXYLIC+ACID'>BST</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1wn6|  PDB=1wn6  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wn6 OCA], [https://pdbe.org/1wn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wn6 RCSB], [https://www.ebi.ac.uk/pdbsum/1wn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wn6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BSD_ASPTE BSD_ASPTE] Catalyzes the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/1wn6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wn6 ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of Blasticidin S Deaminase (BSD) Complexed with Tetrahedral Intermediate of Blasticidin S===
+==See Also==
+*[[Deaminase 3D structures|Deaminase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17959604}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17959604 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17959604}}
-==About this Structure==
-[[1wn6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WN6 OCA].
-==Reference==
-<ref group="xtra">PMID:17959604</ref><ref group="xtra">PMID:10089374</ref><references group="xtra"/>
 [[Category: Aspergillus terreus]]
-[[Category: Blasticidin-S deaminase]]
+[[Category: Large Structures]]
-[[Category: Furuichi, M.]]
+[[Category: Furuichi M]]
-[[Category: Kimura, M.]]
+[[Category: Kimura M]]
-[[Category: Kumasaka, T.]]
+[[Category: Kumasaka T]]
-[[Category: Nakasako, M.]]
+[[Category: Nakasako M]]
-[[Category: Ueki, T.]]
+[[Category: Ueki T]]
-[[Category: Yamaguchi, I.]]
+[[Category: Yamaguchi I]]
-[[Category: Yamamoto, M.]]
+[[Category: Yamamoto M]]
-[[Category: Cytidine deaminase family]]
-[[Category: Hydrolase]]
-[[Category: Tetramer]]
-[[Category: Zinc]]