3h5e: Difference between revisions

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[[Image:3h5e.png|left|200px]]


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==LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis==
The line below this paragraph, containing "STRUCTURE_3h5e", creates the "Structure Box" on the page.
<StructureSection load='3h5e' size='340' side='right'caption='[[3h5e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3h5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H5E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h5e OCA], [https://pdbe.org/3h5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h5e RCSB], [https://www.ebi.ac.uk/pdbsum/3h5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h5e ProSAT]</span></td></tr>
{{STRUCTURE_3h5e| PDB=3h5e |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEUD_MYCTU LEUD_MYCTU] Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h5/3h5e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h5e ConSurf].
<div style="clear:both"></div>


===LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis===
==See Also==
 
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
 
*[[Isopropylmalate isomerase|Isopropylmalate isomerase]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_20938981}}
 
==About this Structure==
[[3h5e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5E OCA].
 
==Reference==
<ref group="xtra">PMID:20938981</ref><ref group="xtra">PMID:19194004</ref><references group="xtra"/>
[[Category: 3-isopropylmalate dehydratase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Geerlof, A.]]
[[Category: Geerlof A]]
[[Category: Manikandan, K.]]
[[Category: Manikandan K]]
[[Category: Weiss, M S.]]
[[Category: Weiss MS]]
[[Category: Amino-acid biosynthesis]]
[[Category: Branched-chain amino acid biosynthesis]]
[[Category: Isopropylmalate isomerase]]
[[Category: Leucine biosynthesis]]
[[Category: Leud]]
[[Category: Lyase]]
[[Category: M tuberculosis]]

Latest revision as of 11:26, 20 March 2024

LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosisLeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis

Structural highlights

3h5e is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LEUD_MYCTU Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3h5e, resolution 2.00Å

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OCA
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