1s6l: Difference between revisions

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[[Image:1s6l.png|left|200px]]


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==Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system==
The line below this paragraph, containing "STRUCTURE_1s6l", creates the "Structure Box" on the page.
<StructureSection load='1s6l' size='340' side='right'caption='[[1s6l]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S6L FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s6l OCA], [https://pdbe.org/1s6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s6l RCSB], [https://www.ebi.ac.uk/pdbsum/1s6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s6l ProSAT]</span></td></tr>
{{STRUCTURE_1s6l|  PDB=1s6l  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system===
[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 15222745 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s6/1s6l_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_15222745}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s6l ConSurf].
[[1s6l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:15222745</ref><ref group="xtra">PMID:15213467</ref><references group="xtra"/>
[[Category: Alkylmercury lyase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Benison, G C.]]
[[Category: Large Structures]]
[[Category: Legault, P.]]
[[Category: Benison GC]]
[[Category: Lello, P Di.]]
[[Category: Di Lello P]]
[[Category: Omichinski, J G.]]
[[Category: Legault P]]
[[Category: Pitts, K E.]]
[[Category: Omichinski JG]]
[[Category: Summers, A O.]]
[[Category: Pitts KE]]
[[Category: Valafar, H.]]
[[Category: Summers AO]]
[[Category: Lyase]]
[[Category: Valafar H]]

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