2vdg: Difference between revisions

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[[Image:2vdg.png|left|200px]]


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==Barley Aldose Reductase 1 complex with butanol==
The line below this paragraph, containing "STRUCTURE_2vdg", creates the "Structure Box" on the page.
<StructureSection load='2vdg' size='340' side='right'caption='[[2vdg]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2vdg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VDG FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1BO:1-BUTANOL'>1BO</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2vdg|  PDB=2vdg |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdg OCA], [https://pdbe.org/2vdg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vdg RCSB], [https://www.ebi.ac.uk/pdbsum/2vdg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vdg ProSAT]</span></td></tr>
 
</table>
===BARLEY ALDOSE REDUCTASE 1 COMPLEX WITH BUTANOL===
== Function ==
 
[https://www.uniprot.org/uniprot/ALDR_HORVU ALDR_HORVU]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2vdg]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDG OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/2vdg_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vdg ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldose Reductase]]
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:18300247</ref><ref group="xtra">PMID:1827067</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Hordeum vulgare]]
[[Category: Hordeum vulgare]]
[[Category: Christensen, C L.]]
[[Category: Large Structures]]
[[Category: Henriksen, A.]]
[[Category: Christensen CL]]
[[Category: Olsen, J G.]]
[[Category: Henriksen A]]
[[Category: Olsen, O.]]
[[Category: Olsen JG]]
[[Category: Pedersen, L.]]
[[Category: Olsen O]]
[[Category: Akr4c]]
[[Category: Pedersen L]]
[[Category: Aldo-keto reductase]]
[[Category: Aldose reductase]]
[[Category: Ligand complex]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Stress response]]

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