Colicin Js: Difference between revisions

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==Synthesis and release==
==Synthesis and release==
The operon for colicin B is encoded on a plasmid in the cytoplasm of the ''E. coli''. This operon also encodes its [[Colicin Immunity Protein]], [[Cji]], to protect the cell from the cytotoxic activities of the colicin, alongside a protein to aid the release of the colicin outside the cell.


==Mechanism of uptake==
==Mechanism of uptake==


==Killing Activities==
The receptor binding domain of the colicin binds to the outer membrane receptor CjrBC<ref> PMID: 12423780 </ref> on the target cell; it is a constitutively expressed protein parasitised by the colicin. The translocation domain then recruits proteins from the [[Ton]] system to translocate the protein across the membrane and into the cytoplasm.
 
==References==
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