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[[Image:3aee.jpg|left|200px]]


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==Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5==
The line below this paragraph, containing "STRUCTURE_3aee", creates the "Structure Box" on the page.
<StructureSection load='3aee' size='340' side='right'caption='[[3aee]], [[Resolution|resolution]] 3.22&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3aee]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AEE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.22&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AT5:3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE'>AT5</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
{{STRUCTURE_3aee|  PDB=3aee  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aee OCA], [https://pdbe.org/3aee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aee RCSB], [https://www.ebi.ac.uk/pdbsum/3aee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aee ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).


===Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5===
==See Also==
 
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3aee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEE OCA].
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Harada, S.]]
[[Category: Harada S]]
[[Category: Honma, T.]]
[[Category: Honma T]]
[[Category: Inaoka, D K.]]
[[Category: Inaoka DK]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kido, Y.]]
[[Category: Kido Y]]
[[Category: Kita, K.]]
[[Category: Kita K]]
[[Category: Mao, J.]]
[[Category: Mao J]]
[[Category: Matsuoka, S.]]
[[Category: Matsuoka S]]
[[Category: Omori, J.]]
[[Category: Omori J]]
[[Category: Osanai, A.]]
[[Category: Osanai A]]
[[Category: Sakamoto, K.]]
[[Category: Sakamoto K]]
[[Category: Sasaki, T.]]
[[Category: Sasaki T]]
[[Category: Shindo, M.]]
[[Category: Shindo M]]
[[Category: Tanaka, A.]]
[[Category: Tanaka A]]

Latest revision as of 13:31, 27 September 2023

Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5

Structural highlights

3aee is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.22Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SDHA_PIG Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).

See Also

3aee, resolution 3.22Å

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