Suppression of RNA Silencing by Viruses: Difference between revisions
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<StructureSection load='' size='450' side='right' scene='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2' caption='Silencing RNA repressor dimer complex with siRNA (PDB code [[1rpu]])'> | |||
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Image:Unremediated1rpuWithPolyview3D.png|left|90px|alt=1rpu image | Image:Unremediated1rpuWithPolyview3D.png|left|90px|alt=1rpu image | ||
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Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. Interestingly, the three proteins in these examples each employ a unique solution to bind the double stranded silencing RNA: [[Tomato aspermy virus protein 2b Suppression of RNA Silencing|one]] interacts with the major groove, [[Flock house virus B2 protein Suppression of RNA Silencing|one]] interacts mainly with the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing|one]] uses "molecular calipers" to measure the size of the silecing RNA. In Proteopedia, there are separate detailed entries for each of these structures: | Three structures, in particular, have provided insight into the basis for the molecular interactions involved in suppression of gene silencing (RNAi) by plant and animal viruses. Interestingly, the three proteins in these examples each employ a unique solution to bind the double stranded silencing RNA: [[Tomato aspermy virus protein 2b Suppression of RNA Silencing|one]] interacts with the major groove, [[Flock house virus B2 protein Suppression of RNA Silencing|one]] interacts mainly with the minor groove, and [[Plant Viral Protein p19 Suppression of RNA Silencing|one]] uses "molecular calipers" to measure the size of the silecing RNA. In Proteopedia, there are separate detailed entries for each of these structures: | ||
*[[Plant Viral Protein p19 Suppression of RNA Silencing]] (<scene name='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2'>click here</scene>, [[1rpu]]) | |||
*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing]] (<scene name='User:Wayne_Decatur/Tomato_aspermy_virus_protein_2b_Suppression_of_RNA_Silencing/View1withtrps/2'>Also click here</scene>, [[1r9f]]) | |||
*[[Flock house virus B2 protein Suppression of RNA Silencing]] (<scene name='User:Wayne_Decatur/Tomato_aspermy_virus_protein_2b_Suppression_of_RNA_Silencing/View1withtrps/2'>Also click here</scene>, [[2zi0]]) | |||
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==Related Structures and Topics== | ==Related Structures and Topics== | ||