3hfb: Difference between revisions

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[[Image:3hfb.png|left|200px]]


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==Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193==
The line below this paragraph, containing "STRUCTURE_3hfb", creates the "Structure Box" on the page.
<StructureSection load='3hfb' size='340' side='right'caption='[[3hfb]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3hfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ML4:4-(5-{[(2-METHYLBIPHENYL-2-YL)METHYL]AMINO}PYRAZIN-2-YL)-L-PHENYLALANINE'>ML4</scene></td></tr>
{{STRUCTURE_3hfb|  PDB=3hfb  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfb OCA], [https://pdbe.org/3hfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfb RCSB], [https://www.ebi.ac.uk/pdbsum/3hfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfb ProSAT]</span></td></tr>
 
</table>
===Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193===
== Function ==
 
[https://www.uniprot.org/uniprot/TPH1_HUMAN TPH1_HUMAN]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[3hfb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hfb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hfb ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Tryptophan hydroxylase]]
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Tryptophan 5-monooxygenase]]
[[Category: Large Structures]]
[[Category: Hunter, M J.]]
[[Category: Hunter MJ]]
[[Category: Swanson, R V.]]
[[Category: Swanson RV]]
[[Category: Tari, L W.]]
[[Category: Tari LW]]
[[Category: Alternative splicing]]
[[Category: Iron]]
[[Category: Metal-binding]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]
[[Category: Phosphoprotein]]
[[Category: Serotonin biosynthesis]]
[[Category: Tryptophan hydroxylase type 1]]

Latest revision as of 12:59, 21 February 2024

Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193

Structural highlights

3hfb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.92Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TPH1_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3hfb, resolution 1.92Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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