2d4v: Difference between revisions

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-[[Image:2d4v.png|left|200px]]
-<!--
+==Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans==
-The line below this paragraph, containing "STRUCTURE_2d4v", creates the "Structure Box" on the page.
+<StructureSection load='2d4v' size='340' side='right'caption='[[2d4v]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2d4v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidithiobacillus_thiooxidans Acidithiobacillus thiooxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D4V FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-{{STRUCTURE_2d4v|  PDB=2d4v  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4v OCA], [https://pdbe.org/2d4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d4v RCSB], [https://www.ebi.ac.uk/pdbsum/2d4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d4v ProSAT]</span></td></tr>
+</table>
-===Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans===
+== Function ==
+[https://www.uniprot.org/uniprot/Q8GAX0_ACITH Q8GAX0_ACITH]
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_17634983}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 17634983 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/2d4v_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_17634983}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[2d4v]] is a 4 chain structure of [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Acidithiobacillus_thiooxidans Acidithiobacillus thiooxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4V OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d4v ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Isocitrate dehydrogenase]]
+*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:17634983</ref><references group="xtra"/>
 [[Category: Acidithiobacillus thiooxidans]]
-[[Category: Imada, K.]]
+[[Category: Large Structures]]
-[[Category: Inagaki, K.]]
+[[Category: Imada K]]
-[[Category: Namba, K.]]
+[[Category: Inagaki K]]
-[[Category: Tamura, T.]]
+[[Category: Namba K]]
-[[Category: Alpha and beta protein]]
+[[Category: Tamura T]]
-[[Category: Isocitrate/isopropylmalate dehydrogenase-like fold]]
-[[Category: Oxidoreductase]]