1cs8: Difference between revisions

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[[Image:1cs8.png|left|200px]]


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==CRYSTAL STRUCTURE OF PROCATHEPSIN L==
The line below this paragraph, containing "STRUCTURE_1cs8", creates the "Structure Box" on the page.
<StructureSection load='1cs8' size='340' side='right'caption='[[1cs8]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1cs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CS8 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
{{STRUCTURE_1cs8|  PDB=1cs8  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cs8 OCA], [https://pdbe.org/1cs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cs8 RCSB], [https://www.ebi.ac.uk/pdbsum/1cs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cs8 ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE OF PROCATHEPSIN L===
== Function ==
 
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[1cs8]] is a 1 chain structure of [[Cathepsin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CS8 OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/1cs8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cs8 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cathepsin]]
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
[[Category: Cathepsin L]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Coulombe, R.]]
[[Category: Large Structures]]
[[Category: Cygler, M.]]
[[Category: Coulombe R]]
[[Category: Hydrolase]]
[[Category: Cygler M]]
[[Category: Inhibition]]
[[Category: Propeptide]]
[[Category: Prosegment]]

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