1n34: Difference between revisions

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-[[Image:1n34.png|left|200px]]
-<!--
+==Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of codon and crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the first codon position==
-The line below this paragraph, containing "STRUCTURE_1n34", creates the "Structure Box" on the page.
+<StructureSection load='1n34' size='340' side='right'caption='[[1n34]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1n34]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N34 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1n34|  PDB=1n34  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n34 OCA], [https://pdbe.org/1n34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n34 RCSB], [https://www.ebi.ac.uk/pdbsum/1n34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n34 ProSAT]</span></td></tr>
+</table>
-===Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of codon and crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the first codon position===
+== Function ==
+[https://www.uniprot.org/uniprot/RS7_THET8 RS7_THET8] One of the primary rRNA binding proteins, it binds directly to 3'-end of the 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center. Binds mRNA and the E site tRNA blocking its exit path in the ribosome. This blockage implies that this section of the ribosome must be able to move to release the deacetylated tRNA.[HAMAP-Rule:MF_00480_B]
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_12464183}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 12464183 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n3/1n34_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_12464183}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1n34]] is a 22 chain structure of [[Ribosomal protein S10]], [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S13]], [[Ribosomal protein S15]], [[Ribosomal protein S17]], [[Ribosomal protein S2]], [[Ribosomal protein S20]], [[Ribosomal protein S3]], [[Ribosomal protein S4]], [[Ribosomal protein THX]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N34 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n34 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Ribosomal protein S10]]
+*[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]]
-*[[Ribosomal protein S11]]
+*[[Ribosome 3D structures|Ribosome 3D structures]]
-*[[Ribosomal protein S12]]
+__TOC__
-*[[Ribosomal protein S13]]
+</StructureSection>
-*[[Ribosomal protein S15]]
+[[Category: Large Structures]]
-*[[Ribosomal protein S17]]
-*[[Ribosomal protein S2]]
-*[[Ribosomal protein S20]]
-*[[Ribosomal protein S3]]
-*[[Ribosomal protein S4]]
-*[[Ribosomal protein THX]]
-*[[Ribosome]]
-==Reference==
-<ref group="xtra">PMID:12464183</ref><references group="xtra"/>
 [[Category: Thermus thermophilus]]
-[[Category: IV, F V.Murphy.]]
+[[Category: Murphy IV FV]]
-[[Category: Ogle, J M.]]
+[[Category: Ogle JM]]
-[[Category: Ramakrishnan, V.]]
+[[Category: Ramakrishnan V]]
-[[Category: Tarry, M J.]]
+[[Category: Tarry MJ]]
-[[Category: 30s ribosomal subunit]]
-[[Category: A site]]
-[[Category: Antibiotic]]
-[[Category: Anticodon]]
-[[Category: Codon]]
-[[Category: Decoding]]
-[[Category: G:u]]
-[[Category: Gu]]
-[[Category: Messenger rna]]
-[[Category: Mismatch]]
-[[Category: Mrna]]
-[[Category: Near-cognate]]
-[[Category: Paromomycin]]
-[[Category: Ribosome]]
-[[Category: Stem-loop]]
-[[Category: Transfer rna]]
-[[Category: Trna]]
-[[Category: Wobble]]