1eg0: Difference between revisions

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[[Image:1eg0.png|left|200px]]


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==FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME==
The line below this paragraph, containing "STRUCTURE_1eg0", creates the "Structure Box" on the page.
<SX load='1eg0' size='340' side='right' viewer='molstar' caption='[[1eg0]], [[Resolution|resolution]] 11.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1eg0]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EG0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
{{STRUCTURE_1eg0|  PDB=1eg0  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eg0 OCA], [https://pdbe.org/1eg0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eg0 RCSB], [https://www.ebi.ac.uk/pdbsum/1eg0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eg0 ProSAT]</span></td></tr>
 
</table>
===FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME===
== Function ==
 
[https://www.uniprot.org/uniprot/RS4_BACSU RS4_BACSU] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.  With S5 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).  S4 represses its own expression; it is not know if this is at the level of translation or of mRNA stability.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/1eg0_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10721991}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1eg0]] is a 15 chain structure of [[Ribosomal protein L6]] and [[Ribosomal protein S15]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EG0 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eg0 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ribosomal protein L6]]
*[[Ribosomal protein L11 3D structures|Ribosomal protein L11 3D structures]]
*[[Ribosomal protein S15]]
*[[Ribosomal protein L6|Ribosomal protein L6]]
 
__TOC__
==Reference==
</SX>
<ref group="xtra">PMID:10721991</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Agrawal, R K.]]
[[Category: Large Structures]]
[[Category: Frank, J.]]
[[Category: Agrawal RK]]
[[Category: Gabashvili, I S.]]
[[Category: Frank J]]
[[Category: Grassucci, R A.]]
[[Category: Gabashvili IS]]
[[Category: Penczek, P.]]
[[Category: Grassucci RA]]
[[Category: Spahn, C M.T.]]
[[Category: Penczek P]]
[[Category: Svergun, D I.]]
[[Category: Spahn CMT]]
[[Category: 70s ribosome]]
[[Category: Svergun DI]]
[[Category: Low resolution model]]

Latest revision as of 10:02, 7 February 2024

FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOMEFITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME

1eg0, resolution 11.50Å

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OCA
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