2gzi: Difference between revisions

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[[Image:2gzi.png|left|200px]]


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==Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)==
The line below this paragraph, containing "STRUCTURE_2gzi", creates the "Structure Box" on the page.
<StructureSection load='2gzi' size='340' side='right'caption='[[2gzi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gzi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GZI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2gzi| PDB=2gzi |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzi OCA], [https://pdbe.org/2gzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gzi RCSB], [https://www.ebi.ac.uk/pdbsum/2gzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gzi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/2gzi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gzi ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)===
==See Also==
 
*[[Colicin 3D structures|Colicin 3D structures]]
 
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
==About this Structure==
__TOC__
2GZI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZI OCA].
</StructureSection>
 
[[Category: Escherichia coli K-12]]
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:10074943</ref><references group="xtra"/>
[[Category: Hemmings AM]]
[[Category: Deoxyribonuclease I]]
[[Category: Kleanthous C]]
[[Category: Escherichia coli k12]]
[[Category: Kolade OO]]
[[Category: Hemmings, A M.]]
[[Category: Kuhlmann UC]]
[[Category: Kleanthous, C.]]
[[Category: Santi PS]]
[[Category: Kolade, O O.]]
[[Category: Kuhlmann, U C.]]
[[Category: Santi, P S.]]
[[Category: 4-helix bundle]]
[[Category: Antibiotic-antibiotic inhibitor complex]]
[[Category: Dnase domain]]
[[Category: Hnh-motif]]
[[Category: Protein-protein complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  6 05:35:48 2010''

Latest revision as of 12:49, 30 August 2023

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)

Structural highlights

2gzi is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IMM9_ECOLX This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2gzi, resolution 1.70Å

Drag the structure with the mouse to rotate

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