3ox3: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 3ox3 is ON HOLD
+==X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values==
+<StructureSection load='3ox3' size='340' side='right'caption='[[3ox3]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ox3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OX3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4X4:N-[2-(2-METHOXY-1H-DIPYRIDO[2,3-A 3,2-E]PYRROLIZIN-11-YL)ETHYL]FURAN-2-CARBOXAMIDE'>4X4</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ox3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ox3 OCA], [https://pdbe.org/3ox3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ox3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ox3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ox3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
-Authors: Pegan, S.D., Sturdy, M., Ferry, G., Delagrange, P., Boutin, J.A., Mesecar, A.D.
+==See Also==
+*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
-Description: X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values.
+== References ==
+<references/>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:58:02 2010''
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Boutin JA]]
+[[Category: Delagrange P]]
+[[Category: Ferry G]]
+[[Category: Mesecar AD]]
+[[Category: Pegan SD]]
+[[Category: Sturdy M]]