3nc6: Difference between revisions

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-{{Seed}}
-[[Image:3nc6.png|left|200px]]
-<!--
+==CYP134A1 1-phenylimidazole bound structure==
-The line below this paragraph, containing "STRUCTURE_3nc6", creates the "Structure Box" on the page.
+<StructureSection load='3nc6' size='340' side='right'caption='[[3nc6]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3nc6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NC6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PIW:1-PHENYL-1H-IMIDAZOLE'>PIW</scene></td></tr>
-{{STRUCTURE_3nc6|  PDB=3nc6  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nc6 OCA], [https://pdbe.org/3nc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nc6 RCSB], [https://www.ebi.ac.uk/pdbsum/3nc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nc6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CYPX_BACSU CYPX_BACSU] Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L-Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA, cLG, cLP) exhibit weaker binding to CYP134A1, but substrates with larger hydrophobic side chains bind in a similar regime to cLL.<ref>PMID:20690619</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/3nc6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nc6 ConSurf].
+<div style="clear:both"></div>
-===CYP134A1 1-phenylimidazole bound structure===
+==See Also==
+*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_20690619}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 20690619 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_20690619}}
-==About this Structure==
-NC6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NC6 OCA].
-==Reference==
-<ref group="xtra">PMID:20690619</ref><references group="xtra"/>
 [[Category: Bacillus subtilis]]
-[[Category: Cryle, M J.]]
+[[Category: Large Structures]]
-[[Category: Schlichting, I.]]
+[[Category: Cryle MJ]]
-[[Category: Cytochrome p450 oxidase]]
+[[Category: Schlichting I]]
-[[Category: Haem protein]]
-[[Category: Oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:20:59 2010''