3ogq: Difference between revisions
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New page: '''Unreleased structure''' The entry 3ogq is ON HOLD Authors: Lin, Y.-C., Perryman, A.L., Elder, J.H., Stout, C.D. Description: Crystal Structure of 6s-98S FIV Protease with Lopinavir ... |
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==Crystal Structure of 6s-98S FIV Protease with Lopinavir bound== | |||
<StructureSection load='3ogq' size='340' side='right'caption='[[3ogq]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ogq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OGQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ogq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ogq OCA], [https://pdbe.org/3ogq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ogq RCSB], [https://www.ebi.ac.uk/pdbsum/3ogq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ogq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. | |||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Feline immunodeficiency virus]] | |||
[[Category: Large Structures]] | |||
[[Category: Elder JH]] | |||
[[Category: Lin Y-C]] | |||
[[Category: Perryman AL]] | |||
[[Category: Stout CD]] | |||
Latest revision as of 13:34, 21 February 2024
Structural highlights
FunctionPOL_FIVPE During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. See Also |
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