3l1g: Difference between revisions

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-{{Seed}}
-[[Image:3l1g.png|left|200px]]
-<!--
+==Human AlphaB crystallin==
-The line below this paragraph, containing "STRUCTURE_3l1g", creates the "Structure Box" on the page.
+<StructureSection load='3l1g' size='340' side='right'caption='[[3l1g]], [[Resolution|resolution]] 3.32&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3l1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L1G FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.32&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_3l1g|  PDB=3l1g  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l1g OCA], [https://pdbe.org/3l1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l1g RCSB], [https://www.ebi.ac.uk/pdbsum/3l1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l1g ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/3l1g_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l1g ConSurf].
+<div style="clear:both"></div>
-===Human AlphaB crystallin===
+==See Also==
+*[[Crystallin 3D structures|Crystallin 3D structures]]
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-<!--
+__TOC__
-The line below this paragraph, {{ABSTRACT_PUBMED_20440841}}, adds the Publication Abstract to the page
+</StructureSection>
-(as it appears on PubMed at http://www.pubmed.gov), where 20440841 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_20440841}}
-==About this Structure==
-L1G is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1G OCA].
-==Reference==
-<ref group="xtra">PMID:20440841</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Cascio, D.]]
+[[Category: Large Structures]]
-[[Category: Eisenberg, D.]]
+[[Category: Cascio D]]
-[[Category: Laganowsky, A.]]
+[[Category: Eisenberg D]]
-[[Category: Sawaya, M R.]]
+[[Category: Laganowsky A]]
-[[Category: Chaperone]]
+[[Category: Sawaya MR]]
-[[Category: Crystallin]]
-[[Category: Eye lens protein]]
-[[Category: Lens transparency]]
-[[Category: Polydispersity]]
-[[Category: Protein aggregation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 15:52:45 2010''