3nj5: Difference between revisions
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New page: '''Unreleased structure''' The entry 3nj5 is ON HOLD Authors: Yin , H.S., Chen, Y.W. Description: Crystal structure of chicken IL-1 hydrophobic cavity mutant 157 ''Page seeded by [htt... |
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==Crystal structure of chicken IL-1 hydrophobic cavity mutant 157== | |||
<StructureSection load='3nj5' size='340' side='right'caption='[[3nj5]], [[Resolution|resolution]] 1.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3nj5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJ5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nj5 OCA], [https://pdbe.org/3nj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nj5 RCSB], [https://www.ebi.ac.uk/pdbsum/3nj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nj5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] | |||
==See Also== | |||
*[[Interleukin 3D structures|Interleukin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gallus gallus]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen YW]] | |||
[[Category: Yin HS]] | |||
Latest revision as of 13:00, 14 February 2024
Crystal structure of chicken IL-1 hydrophobic cavity mutant 157Crystal structure of chicken IL-1 hydrophobic cavity mutant 157
Structural highlights
FunctionO73909_CHICK Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] See Also |
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