User:Daniel Seeman/DELETE: Difference between revisions

Latest revision as of 13:35, 23 May 2018

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-<applet load='Caspmorph.pdb' size='300' frame='true' align='right' caption='Toggle between active site inhibitor bound and allosterically inhibited caspase-7' />
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-=== Forms of Caspase-7 ===
-*<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/1f1j/1'>Caspase-7 bound to dead-end substrate mimic DEVD-CHO</scene>, trapping protein in active/substrate bound conformation.
-*<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/1shj-234234/1'>Caspase-7 bound to allosteric inhibitor DICA through CYS290</scene> trapping protein in a form incompatible with substrate binding.
-*<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/Morph1/1'>Conformational change between substrate bound and substrate incompatible forms</scene> of Caspase-7.
-=== Molecular Playground banner ===
-'''Molecular Playground banner:''' Conformational Dynamics between active and allosterically inhibited caspase-7 elucidate the mechanism of allostery in this important class of cysteine proteases.