163d: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 {{Theoretical_model}}
-{{Seed}}
-[[Image:163d.png|left|200px]]
-<!--
+==A THREE-DIMENSIONAL MODEL OF THE REV BINDING ELEMENT OF HIV- 1 DERIVED FROM ANALYSES OF IN VITRO SELECTED VARIANTS==
-The line below this paragraph, containing "STRUCTURE_163d", creates the "Structure Box" on the page.
+<StructureSection load='163d' size='340' side='right'caption='[[163d]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=163D FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=163d FirstGlance], [https://www.ebi.ac.uk/pdbsum/163d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=163d ProSAT]</span></td></tr>
--->
+</table>
-{{STRUCTURE_163d|  PDB=163d  |  SCENE=  }}
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Coordinated variations in the sequence of the Rev-binding element of HIV-1, identified by in vitro genetic selections, have been used as distance and conformational constraints for molecular modelling. Three-dimensional models of the wild-type Rev-binding element and several, evolved RNA ligands (aptamers) have been constructed. These models demonstrate that non-Watson-Crick pairings open the major groove allowing access of an alpha-helical peptide from Rev, and explain why some selected RNA sequences can bind Rev more tightly than others.
-===A THREE-DIMENSIONAL MODEL OF THE REV BINDING ELEMENT OF HIV- 1 DERIVED FROM ANALYSES OF IN VITRO SELECTED VARIANTS===
+A three-dimensional model of the Rev-binding element of HIV-1 derived from analyses of aptamers.,Leclerc F, Cedergren R, Ellington AD Nat Struct Biol. 1994 May;1(5):293-300. PMID:7664035<ref>PMID:7664035</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_7664035}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 163d" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 7664035 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_7664035}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Theoretical Model]]
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=163D OCA].
+[[Category: Large Structures]]
-==Reference==
-<ref group="xtra">PMID:7664035</ref><references group="xtra"/>
 [[Category: Cedergren, R J]]
 [[Category: Ellington, A D]]
 [[Category: Leclerc, F]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  8 08:31:02 2010''