1gwt: Difference between revisions

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[[Image:1gwt.gif|left|200px]]<br /><applet load="1gwt" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1gwt, resolution 1.70&Aring;" />
'''RECOMBINANT HORSERADISH PEROXIDASE C1A PHE221MET'''<br />


==About this Structure==
==RECOMBINANT HORSERADISH PEROXIDASE C1A PHE221MET==
1GWT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana] with CA, NA, HEM and FER as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] Known structural/functional Site: <scene name='pdbsite=AC1:Fer Binding Site For Residue A 701'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWT OCA].  
<StructureSection load='1gwt' size='340' side='right'caption='[[1gwt]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1gwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GWT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FER:3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC+ACID'>FER</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gwt OCA], [https://pdbe.org/1gwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gwt RCSB], [https://www.ebi.ac.uk/pdbsum/1gwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gwt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PER1A_ARMRU PER1A_ARMRU] Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/1gwt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gwt ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Horseradish peroxidase|Horseradish peroxidase]]
__TOC__
</StructureSection>
[[Category: Armoracia rusticana]]
[[Category: Armoracia rusticana]]
[[Category: Peroxidase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Brissett N]]
[[Category: Brissett, N.]]
[[Category: Gajhede M]]
[[Category: Gajhede, M.]]
[[Category: Henriksen A]]
[[Category: Henriksen, A.]]
[[Category: CA]]
[[Category: FER]]
[[Category: HEM]]
[[Category: NA]]
[[Category: oxidoreductase]]
[[Category: peroxidase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 15:43:07 2007''

Latest revision as of 15:09, 13 December 2023

RECOMBINANT HORSERADISH PEROXIDASE C1A PHE221METRECOMBINANT HORSERADISH PEROXIDASE C1A PHE221MET

Structural highlights

1gwt is a 1 chain structure with sequence from Armoracia rusticana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PER1A_ARMRU Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1gwt, resolution 1.70Å

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