3lon: Difference between revisions

New page: '''Unreleased structure''' The entry 3lon is ON HOLD Authors: Arasappan, A., Bennett F., Bogen, S. L., Blackman, M., Chen, K., Hendrata, S.,Huang,Y., Huelgas,R. M.,Nair, L., Padilla, A....
 
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'''Unreleased structure'''


The entry 3lon is ON HOLD
==HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir==
<StructureSection load='3lon' size='340' side='right'caption='[[3lon]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3lon]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LON FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>NNA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lon OCA], [https://pdbe.org/3lon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lon RCSB], [https://www.ebi.ac.uk/pdbsum/3lon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lon ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9ELS8_9HEPC Q9ELS8_9HEPC]


Authors: Arasappan, A., Bennett F., Bogen, S. L., Blackman, M., Chen, K., Hendrata, S.,Huang,Y., Huelgas,R. M.,Nair, L., Padilla, A.I., Pan, W., Pike, R., Pinto, P., Ruan, S., Sannigrahi, M., Velaquez, F., Vibulbhan, B., Wu, W., Yang, W., Saksena, A.K., Girijavall
==See Also==
 
*[[Virus protease 3D structures|Virus protease 3D structures]]
Description: HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir
__TOC__
 
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 17:00:36 2010''
[[Category: Hepatitis C virus genotype 1a]]
[[Category: Large Structures]]
[[Category: Prongay AJ]]

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