3ifk: Difference between revisions

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-{{Seed}}
-[[Image:3ifk.jpg|left|200px]]
-<!--
+==Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90==
-The line below this paragraph, containing "STRUCTURE_3ifk", creates the "Structure Box" on the page.
+<StructureSection load='3ifk' size='340' side='right'caption='[[3ifk]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ifk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-{{STRUCTURE_3ifk|  PDB=3ifk  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ifk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ifk OCA], [https://pdbe.org/3ifk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ifk RCSB], [https://www.ebi.ac.uk/pdbsum/3ifk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ifk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CALM1_RAT CALM1_RAT] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/3ifk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ifk ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90===
+==See Also==
+*[[Calmodulin 3D structures|Calmodulin 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-IFK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFK OCA].
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Newman, R A.]]
+[[Category: Newman RA]]
-[[Category: Shea, M A.]]
+[[Category: Shea MA]]
-[[Category: Witt, T J.]]
+[[Category: Witt TJ]]
-[[Category: Acetylation]]
-[[Category: Calcium]]
-[[Category: Calmodulin]]
-[[Category: Ef hand motif]]
-[[Category: Isopeptide bond]]
-[[Category: Metal binding protein]]
-[[Category: Methylation]]
-[[Category: N-domain]]
-[[Category: N-terminal domain]]
-[[Category: Phosphoprotein]]
-[[Category: Phosphorylation]]
-[[Category: Residues 1-90]]
-[[Category: Ubl conjugation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 13:51:57 2009''